526 research outputs found
Changing ideas about others' intentions: updating prior expectations tunes activity in the human motor system
Predicting intentions from observing another agentâs behaviours is often thought to depend on motor resonance â i.e., the motor systemâs response to a perceived movement by the activation of its stored motor counterpart, but observers might also rely on prior expectations, especially when actions take place in perceptually uncertain situations. Here we assessed motor resonance during an action prediction task using transcranial magnetic stimulation to probe corticospinal excitability (CSE) and report that experimentally-induced updates in observersâ prior expectations modulate CSE when predictions are made under situations of perceptual uncertainty. We show that prior expectations are updated on the basis of both biomechanical and probabilistic prior information and that the magnitude of the CSE modulation observed across participants is explained by the magnitude of change in their prior expectations. These findings provide the first evidence that when observers predict othersâ intentions, motor resonance mechanisms adapt to changes in their prior expectations. We propose that this adaptive adjustment might reflect a regulatory control mechanism that shares some similarities with that observed during action selection. Such a mechanism could help arbitrate the competition between biomechanical and probabilistic prior information when appropriate for prediction
The experience of falls and balance impairment for people with Charcot-Marie-Tooth disease
People with Charcot Marie Tooth disease (CMT) have impairments of balance and may fall more frequently than those without the condition. This qualitative study aimed to explore the experiences of falling and poor balance through focus group interviews.
Participants were recruited through local and national meetings of the CMT United Kingdom support group. Three focus groups took place, including 25 adults with CMT in total.
Thematic analysis revealed five main themes: frequent falling; cognitive burden of walking; environmental issues; external support; getting off the floor; perception of others. Participants described the physical issues of poor balance and falling, such as frequency, challenging physical environments and difficulty getting up after a fall. In addition, fear and embarrassment were discussed along with the impact on daily activities and participation.
Physical and psychological factors need to be considered when designing falls management interventions for this group
Remembering Your Roots: The Role of Horticulture Therapy in People Living with Dementia
Introduction: Dementia is a debilitating disease affecting over 50 million people. Major challenges facing patients with dementia lie in the impact of the behavioral and psychological symptoms of dementia (BPSD). The American Geriatrics Society and Dementia Action Alliance recommend against the use of antipsychotics as first-line treatment. Antipsychotics often fail to treat BPSD whereas nonmedication practices such as horticulture therapy may lessen BPSD. Guideline evidence has provided a unique opportunity for public health officials to assist in filling this vital role in the approach to BPSD management.Methods: Several studies and meta-analyses were reviewed to determine the effectiveness of horticulture therapy in managing BPSD, and evidence supports horticulture therapy as an effective method of addressing BPSD.Results: The benefits of horticulture therapy extend beyond addressing only BPSD; through multisensory stimulation, patients have increased physical activity, reduced stress, and improved sleep. Horticulture therapy has been shown to decrease the sense of loss and reestablish the patient in a familiar nurturing role, providing the patient with a sense of purpose.Conclusion: Stakeholders within the public health sector are strategically positioned to implement evidence-based interventions that address the unmet needs for the care of dementia within the community
Educators' experiences and perspectives of child weight discussions with parents in primary school settings.
From Europe PMC via Jisc Publications RouterHistory: ppub 2022-04-01, epub 2022-04-22Publication status: PublishedFunder: Academy of Medical Sciences; Grant(s): HOP001\1062BackgroundThe role of schools in addressing rising childhood obesity levels has been acknowledged, and numerous diet- and physical activity-related interventions exist. Aside from formal interventions, opportunistic parent-educator conversations about child weight can arise, particularly in primary school settings, yet little is known about how useful these are. This study aimed to understand the utility of child weight related conversations with parents through exploring educators' experiences and perspectives.MethodsThis qualitative study consisted of semi-structured interviews conducted with primary school teaching staff in the United Kingdom (Nâ=â23), recruited through purposive and subsequent snowball sampling. Interviews were audio-recorded, transcribed, and analysed using thematic analysis.ResultsParticipants identified opportunities and need for child weight discussions in schools. However, conversations were prevented by the indirect and sensitive nature of conversations, and educators' professional identity beliefs. Using pre-existing face-to-face opportunities, good parent-teacher relationships and holistic approaches to child health and wellbeing were reported as important in optimising these conversations.ConclusionsWhilst educator-parent child weight discussions are necessary, discussions are highly challenging, with contradictory views on responsibility sometimes resulting in avoidance. Educators' roles should be clarified, and communication training tailored to increase teacher confidence and skills. Current social distancing will likely reduce opportunistic encounters, highlighting a need to further improve communication routes
The distribution and population status of Nesiergus insulanus (Araneae: Theraphosidae: Ischnocolinae) on Frégate Island, Seychelles
The theraphosid Nesiergus insulanus is a member of a genus endemic to the Seychelles archipelago. Very little is known about the finer-scale distribution, density, and total population size of the species, knowledge of which is essential for conservation purposes. We used transect sampling to estimate these variables on Frégate Island. We show that the species is widely distributed, but geographically restricted as a result of fragmentation due to human activity. Where found, densities can be very high (>100 m-2). The total population on the island was estimated to be well over 100,000, although limitations to dispersal ability may be of conservation concern.http://wiki.britishspiders.org.uk/index.php5?title=Publications/Arachnologyam2014ab201
Aspects of the ecology and behaviour of the Seychelles theraphosid Nesiergus insulanus (Arachnida : Araneae : Theraphosidae)
Aspects of the ecology and life history of the little known theraphosid Nesiergus insulanus are determined
on Frégate Island in the Seychelles archipelago. The general behaviour of this species is revealed to be
comparable to that of other theraphosids, with field and captive observations establishing that they are a
generalist and opportunistic species. The defensive behaviour of the species is determined to be based
primarily on the avoidance of conflict situations, with overt aggressive behaviour seldom displayed. Although
the opportunistic existence that this species has developed is probably obligatory due to their sedentary
lifestyle and limited availability of resources, this behaviour nonetheless allows the species to occupy diverse
habitats and exploit niches unavailable to more specialized species.http://africaninvertebrates.org2016-12-30am201
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A Headset Method for Measuring the Visual Temporal Discrimination Threshold in Cervical Dystonia
Background: The visual temporal discrimination threshold (TDT) is the shortest time interval at which one can determine two stimuli to be asynchronous and meets criteria for a valid endophenotype in adultâonset idiopathic focal dystonia, a poorly penetrant disorder. Temporal discrimination is assessed in the hospital laboratory; in unaffected relatives of multiplex adultâonset dystonia patients distance from the hospital is a barrier to data acquisition. We devised a portable headset method for visual temporal discrimination determination and our aim was to validate this portable tool against the traditional laboratoryâbased method in a group of patients and in a large cohort of healthy controls.
Methods: Visual TDTs were examined in two groups 1) in 96 healthy control participants divided by age and gender, and 2) in 33 cervical dystonia patients, using two methods of data acquisition, the traditional tableâtop laboratoryâbased system, and the novel portable headset method. The order of assessment was randomized in the control group. The results obtained by each technique were compared.
Results: Visual temporal discrimination in healthy control participants demonstrated similar age and gender effects by the headset method as found by the tableâtop examination. There were no significant differences between visual TDTs obtained using the two methods, both for the control participants and for the cervical dystonia patients. BlandâAltman testing showed good concordance between the two methods in both patients and in controls.
Discussion: The portable headset device is a reliable and accurate method for visual temporal discrimination testing for use outside the laboratory, and will facilitate increased TDT data collection outside of the hospital setting. This is of particular importance in multiplex families where data collection in all available members of the pedigree is important for exome sequencing studies
Results from the Sweden 2016 Report Card on Physical Activity for Children and Youth
Background: The Sweden 2016 Report Card on Physical Activity (PA) for Children and Youth is a unique compilation of the existing physical and health related data in Sweden. The aim of this paper is to summarize the procedure and results from the report card. Methods: Nationally representative surveys and individual studies between 2005-2015 were included. Eleven PA and health indicators were graded using the Active Healthy Kids Canada grading system. Grades were assigned based on the percentage of children/youth meeting a defined benchmark (A: 81-100%, B: 61-80%, C: 41-60%, D: 21-40%, F: 0-20%, or incomplete (INC). Results: The assigned grades were: Overall Physical Activity, D; Organized Sport Participation, B+; Active Play, INC; Active Transportation, C+; Sedentary Behaviors, C; Family and Peers, INC; School, C+; Community and the Built Environment, B; Government Strategies and Investments, B; Diet, C-; and Obesity, D. Conclusion: The included data provides some support that overall PA is too low and sedentary behavior is too high for almost all age groups in Sweden, even with the many national policies as well as an environment that is favorable to the promotion of PA
Educatorsâ experiences and perspectives of child weight discussions with parents in primary school settings
From Springer Nature via Jisc Publications RouterHistory: received 2021-03-23, accepted 2021-08-29, registration 2022-04-11, pub-electronic 2022-04-22, online 2022-04-22, collection 2022-12Publication status: PublishedFunder: The Academy of Medical Sciences; Grant(s): HOP001\1062, HOP001\1062Abstract: Background: The role of schools in addressing rising childhood obesity levels has been acknowledged, and numerous diet- and physical activity-related interventions exist. Aside from formal interventions, opportunistic parent-educator conversations about child weight can arise, particularly in primary school settings, yet little is known about how useful these are. This study aimed to understand the utility of child weight related conversations with parents through exploring educatorsâ experiences and perspectives. Methods: This qualitative study consisted of semi-structured interviews conducted with primary school teaching staff in the United Kingdom (N = 23), recruited through purposive and subsequent snowball sampling. Interviews were audio-recorded, transcribed, and analysed using thematic analysis. Results: Participants identified opportunities and need for child weight discussions in schools. However, conversations were prevented by the indirect and sensitive nature of conversations, and educatorsâ professional identity beliefs. Using pre-existing face-to-face opportunities, good parent-teacher relationships and holistic approaches to child health and wellbeing were reported as important in optimising these conversations. Conclusions: Whilst educator-parent child weight discussions are necessary, discussions are highly challenging, with contradictory views on responsibility sometimes resulting in avoidance. Educatorsâ roles should be clarified, and communication training tailored to increase teacher confidence and skills. Current social distancing will likely reduce opportunistic encounters, highlighting a need to further improve communication routes
Terahertz spectroscopy of 2,4,6-trinitrotoluene molecular solids from first principles
We present a computational analysis of the terahertz spectra of the monoclinic and the orthorhombic polymorphs of 2,4,6-trinitrotoluene.
Very good agreement with experimental data is found when using density functional theory that includes
TkatchenkoâScheffler pair-wise dispersion interactions. Furthermore, we show that for these polymorphs the theoretical results are
only weakly affected by many-body dispersion contributions. The absence of dispersion interactions, however, causes sizable shifts
in vibrational frequencies and directly affects the spatial character of the vibrational modes. Mode assignment allows for a distinction
between the contributions of the monoclinic and orthorhombic polymorphs and shows that modes in the range from 0 to
ca. 3.3 THz comprise both inter- and intramolecular vibrations, with the former dominating below ca. 1.5 THz. We also find that
intramolecular contributions primarily involve the nitro and methyl groups. Finally, we present a prediction for the terahertz spectrum
of 1,3,5-trinitrobenzene, showing that a modest chemical change leads to a markedly different terahertz spectrum
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